Description
Product Characteristics:
Aliases: NSMAF antibody, FANProtein FAN antibody, Factor associated with neutral sphingomyelinase activation antibody, Factor associated with N-SMase activation antibody
Target Information: This gene encodes a WD-repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF-mediated activation of neutral sphingomyelinase and may play a role in regulating TNF-induced cellular responses such as inflammation. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2009]